Not connected to a subject
To introduces the thing that lacks relevance.
Irrelevant is normally followed by to. Other prepositions usually express different sentence relationships.
Use irrelevant to for something not connected to a subject or purpose. In, for, of, and as usually belong to other sentence structures.
These forms are not interchangeable. Choose the construction by meaning, not by which preposition appears most often.
To introduces the thing that lacks relevance.
In introduces a setting rather than the normal complement.
The same subject can take different constructions because each sentence answers a different question.
Some combinations appear in real text but do not mean what learners often assume.
Of is not the standard preposition after irrelevant.
✕ This detail is irrelevant of the issue. ✓ This detail is irrelevant to the issue.To links irrelevant with a subject; in introduces a context.
✕ The point is irrelevant in the debate topic. ✓ The point is irrelevant to the debate topic.Choose the expression that matches the intended meaning.
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Irrelevant to is the standard and most common pattern.
Yes. In introduces the context where something lacks importance.
No. Use irrelevant to or regardless of depending on the meaning.
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