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mercaptopurine

NOUN
  1. a drug (trade name Purinethol) that interferes with the metabolism of purine and is used to treat acute lymphocytic leukemia

How To Use mercaptopurine In A Sentence

  • The intramuscular ld50 of mercaptopurine was licensed to suffer 480 mg/kg in the what is allopurinol for and 425 mg/kg in the rat. Wii-volution
  • The result was azathioprine (1957) which replaced mercaptopurine as an inhibitor of the immune response. Physiology or Medicine 1988 - Press Release
  • The liposomal ld50 of mercaptopurine was compared to fold 480 mg/kg in the and 425 mg/kg in the rat. Wii-volution
  • The data support the safety of 6-mercaptopurine and azathioprine use in the treatment of pediatric patients with ulcerative colitis; side effects were minimal and reversible. IBD clinical studies: drug comparisons
  • They were then analyzed for the development of side effects, the indication to use 6-mercaptopurine and azathioprine and the ability to discontinue corticosteroid use in those patients taking 5-acetylsalicylic acid products who were corticosteroid-dependent or whose disease was refractory to treatment. IBD clinical studies: drug comparisons
  • When a 12-year-old boy from Illinois with ALL arrived at St. Jude in 2001, Pui administered everything but the kitchen sink: the drugs prednisone, vincristine, daunorubicin, and asparaginase, followed by cyclophosphamide, cytarabine, and mercaptopurine. Curing Cancer
  • When a 12-year-old boy from Illinois with ALL arrived at St. Jude in 2001, Pui administered everything but the kitchen sink: the drugs prednisone, vincristine, daunorubicin, and asparaginase, followed by cyclophosphamide, cytarabine, and mercaptopurine. Curing Cancer
  • The median time to discontinuation of corticosteroid after initiation of 6-mercaptopurine and azathioprine therapy was 8.4 months. IBD clinical studies: drug comparisons
  • Tisupurine is more water-soluble than mercaptopurine (6-MP). Easily release 6-MP under acidic condition or the existing of sulfhydryl compounds, has selectivity to tumor tissue.
  • They prevented rabbits from producing antibody against human serum albumin by treating them for two weeks with the antimetabolite, 6-Mercaptopurine. Joseph E. Murray - Nobel Lecture
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